SKF 91488 dihydrochloride CAS: 68643-23-2
MF: C7H17N3S•2HCl
MW: 248.22
A strong inhibitor of histamine N-methyltransferase.

SKF 91488 dihydrochloride (CAS 68643-23-2)

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Alternate Names: 4-(N,N-Dimethylamino)butylisothiourea dihydrochloride
Application: SKF 91488 dihydrochloride is a strong inhibitor of histamine N-methyltransferase
CAS Number: 68643-23-2
Molecular Weight: 248.22
Molecular Formula: C7H17N3S•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

SKF 91488 dihydrochloride is a homologue of dimaprit is a strong inhibitor of HNMT (histamine N-methyltransferase,) with no histamine agonist activity.


References

1. Beaven, M.A. and Shaff, R.E. 1979. Biochem.Pharmacol. 28: 183-188.
2. Beaven, M.A. and Shaff, R.E. 1979. Agents Actions. 9: 455-460.
3. Ohrui, T., et al. 1992. J. Pharmacol. Exp. Ther. 261: 1268-1272.
4. Malmberg-Aiello, P., et al. 1997. Naunyn-Schmied. Arch. Pharmacol. 355: 354-360.

Physical State :
Solid
Solubility :
Soluble in DMSO (75 mM).
Storage :
Store at room temperature
Refractive Index :
n20D 1.53 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD00153870
SMILES :
CN(C)CCCCSC(=N)N.Cl.Cl

Download SDS (MSDS)

Certificate of Analysis

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