SKF-75670 hydrobromideAn atypical D1 dopamine receptor agonist

SKF-75670 hydrobromide (CAS 62717-63-9)

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Application: An atypical D1 dopamine receptor agonist
CAS Number: 62717-63-9
Purity: >98%
Molecular Weight: 350.25
Molecular Formula: C17H19NO2•HBr
* Refer to Certificate of Analysis for lot specific data (including water content).
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SKF-75670 hydrobromide is a atypical D1DR (dopamine receptor) agonist. It displays antagonist activity in vitro and agonist activity in vivo.

Physical State :
Solid
Solubility :
Soluble in DMSO (12 mg/ml). Insoluble in water.
Storage :
Store at room temperature
Melting Point :
270-270.5° C
Boiling Point :
450.1° C at 760 mmHg
Refractive Index :
n20D ~1.62 (Predicted)
IC50 :
Rattus norvegicus: IC50 = 0.63 µM; HTR2A: EC5050 = 1.37 µM (mouse 5-hydroxytryptamine)
Ki Data :
Dopamine D1 receptor: Ki= 8.8 nM (human); Dopamine D2 receptor: Ki= 1.9 µM (human)
pK Values :
pKa: 10.14 (Predicted), pKb: 8.31 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
173870
MDL Number :
MFCD11045981
SMILES :
CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)O.Br

Download SDS (MSDS)

Certificate of Analysis

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