Anti-SHOX2 Antibody (JK-6E) is a mouse monoclonal IgG2a (kappa light chain) SHOX2 antibody provided at 100 µg/ml
raised against recombinant SHOX2 of human origin
recommended for detection of SHOX2 of mouse, rat and human origin by WB, IP and ELISA
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of SHOX2 (JK-6E): sc-81955.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for SHOX2 Antibody (JK-6E) for WB applications. These reagents are now offered in bundles with SHOX2 Antibody (JK-6E) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
SHOX2 Antibody (JK-6E) is a high quality monoclonal SHOX2 antibody (also designated SHOX2 antibody) suitable for the detection of the SHOX2 protein of mouse, rat and human origin. SHOX2 Antibody (JK-6E) is available as the non-conjugated anti-SHOX2 antibody. Homeodomain proteins (HP) are transcriptional regulators that coordinate the expression of genes involved in development, differentiation and cellular transformation. HPs are characterized by a conserved domain of 60 amino acid residues that recognize and bind a site in the regulatory region of the target gene. SHOX2, also designated SHOT, is a human paired-related homeobox gene with two known isoforms, SHOX2A and SHOX2B, which are products of alternative splicing. The SHOX2A and SHOX2B isoforms differ in N-terminal residues and an alternatively-spliced C-terminal exon. Both isoforms contain a C-terminal OAR domain, a motif characteristic of craniofacially-expressed homeodomain proteins. Transcripts of Og12X, the mouse ortholog of SHOX2, have been isoloated in the aorta, female genitalia, diencephalon, mesencephalon, myelencephalon, nasal capsula, palate, eyelid and limbs of developing mouse embryo. Og12x localization and expression patterns suggest that SHOX2 may play a role in the pathology of Cornelia de Lange syndrome, a multisystem disorder that is characterized by somatic and cognitive retardation, characteristic facial features and limb abnormalities.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.