Anti-Septin 3 Antibody (G-6) is a mouse monoclonal IgG2b (kappa light chain) Septin 3 antibody provided at 200 µg/ml
raised against amino acids 1-50 of Septin 3 of human origin
Anti-Septin 3 Antibody (G-6) is recommended for detection of Septin 3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-Septin 3 Antibody (G-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Septin 3 (G-6): sc-74431.
m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Septin 3 Antibody (G-6) for WB and IHC(P) applications. These reagents are now offered in bundles with Septin 3 Antibody (G-6) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Septin 3 Antibody (G-6) is a high quality monoclonal Septin 3 antibody (also designated Sept3 antibody) suitable for the detection of the Septin 3 protein of mouse, rat and human origin. Septin 3 Antibody (G-6) is available as both the non-conjugated anti-Septin 3 antibody form, as well as multiple conjugated forms of anti-Septin 3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. At least three septins (Septin 1, 2 and 4) are associated with a tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Septin 3 (G-Septin), a GTP-binding protein, is highly expressed in brain and is regulated by protein kinase G in neurons. The human SEPT4 (H5/PNUTL2/CDCREL-2) gene encodes ARTS (for apoptosis-related protein in the TGF-β signaling pathway), which is expressed in many cells and acts to enhance cell death induced by TGF-β or, to a lesser extent, by other apoptotic agents. ARTS is localized to mitochondria and translocates to the nucleus when apoptosis occurs. Septin 5 is a major form of the CDCREL-1 septin in the adult neocortex of mammals. Human Septin 6 protein contains an ATP-GTP binding motif and three nuclear targeting sequences in its C-terminus. Septin 6 is the third septin member that is fused to the MLL protein, in addition to hCDCREL and MSF.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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