SELB Antibody (F-4): sc-365707

SELB Antibody (F-4) is a mouse monoclonal IgG1 antibody that detects SELB (selenocysteine-specific elongation factor) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SELB is a 596 amino acid protein that plays a crucial role in the translation process by facilitating the incorporation of selenocysteine into proteins, which is essential for the proper functioning of various selenoproteins that are vital for antioxidant defense and redox regulation in cells. The localization of SELB in both the nucleus and cytoplasm underscores its importance in cellular processes, as SELB is involved in the synthesis of proteins that are critical for maintaining cellular homeostasis and responding to oxidative stress. The gene encoding SELB is located on human chromosome 3, a region associated with several key tumor suppressor genes and genetic diseases, highlighting the potential implications of SELB in cancer biology and hereditary disorders. Anti-SELB antibody (F-4) is an invaluable tool for researchers investigating the role of selenoproteins in health and disease, providing insights into the molecular mechanisms underlying various biological processes.

The preferred SELB antibody is SELB Antibody (G-9): sc-166521.