Sedanolide is an inducer of glutathione S-transferases (GSTs) and inhibitor of chemically induced carcinogenesis. It was shown to inhibit cyclooxygenase-1 and -2 (Cox-1 and -2) as well as topoisomerase I and topoisomerase II (Topo I and Topo II). Sedanolide is mosquitocidal, nematicidal and antifungal.
1. Zheng, G.Q., et al. 1993. Nutr. Cancer. 19: 77-86. PMID: 8446516 2. Momin, R.A., et al. 2001. J. Agric. Food Chem. 49: 142-145. PMID: 11305251 3. Woods, J.A., et al. 2001. In. Vitr. Mol. Toxicol. 14: 233-240. PMID: 11846995 4. Momin, R.A. and Nair, M.G. 2002. Phytomedicine. 9: 312-318. PMID: 12120812
Apium graveolens L.
Soluble in 100% ethanol , acetonitrile, methanol, and ethyl acetate.
Store at -20° C
47.53° C (Predicted)
~342.0° C at 760 mmHg (Predicted)
n20D 1.5 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Download SDS (MSDS)
Certificate of Analysis
Adobe Acrobat Reader is required to reliably view, print and comment on PDF documents
Is SC-205972 trans or cis?
Asked by: Jz28sail
Thank you for your question. For the compound, sc-205972, we do not characterize whether it is cis or trans. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing email@example.com, or using the Live Chat function on our website.
Rated 5 out of
Momin et al (PubMed ID 11305251) found thatMomin et al (PubMed ID 11305251) found that sedanolide was a prostaglandin H endoperoxide synthase- (COX-1) and Cox-II inhibitor at pH 7 and also inhibited topoisomerase I/II activity. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.Hide
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.