Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US, Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been receivedPlease note: We can not ship to PO boxes
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal health products, bulky and/or heavy items
SCYL1 (SCY1-like protein 1), also known as NTKL (N-terminal kinase-like protein), CVAK90 (coated vesicle-associated kinase of 90 kDa), GKLP, TAPK, TEIF or TRAP (telomerase regulation-associated protein), is an 808 amino acid protein that belongs to the protein kinase superfamily. SCYL1 contains three heat domains and one protein kinase domain, which is thought to be catalytically inactive. SCYL1 regulates COPI-mediated traffic and interacts with COPA, COPB1, COPB2, AP2B1 and GORAB. SCYL1 undergoes alternative splicing events to produce six isoforms. Isoform 6 localizes to the nucleus where it acts as a transcriptional activator and binds three GC-rich sites (box A, B and C) in the region of the beta-polymerase and TERT promoter. Isoforms 1, 2 and 3 are known to localize to the cytoplasm. The gene encoding SCYL1 maps to human chromosome 11.
|Species||Gene Name||Gene ID||Chromosome Location||Isoform (mRNA) Accession #||Protein Accession #||OMIM™ Number|
|Human||SCYL1||57410||11q13.1||XM_005274118, XM_005274120, XM_005274121, XM_017018029, XM_017018030, XM_017018031, XM_017018032, XM_017018033, NM_001048218, NM_020680||Q96KG9||607982|
|Mouse||Scyl1||78891||19 A||XM_006531856, XM_006531857, NM_023912||Q9EQC5||N/A|