SCSPotent and selective partial inhibitor of β1-containing GABAA receptors

SCS (CAS 3232-36-8)

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Synonym: Salicylidene salicylhydrazide
Application: Potent and selective partial inhibitor of β1-containing GABAA receptors
CAS Number: 3232-36-8
Molecular Weight: 256.26
Molecular Formula: C14H12N2O3
* Refer to Certificate of Analysis for lot specific data (including water content).
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SCS is a potent and selective partial inhibitor of β1-containing GABAA receptors (IC50 values are 4.5, 5.3 and 7.9 nM at α2β1γ1θ, α2β1γ1 and α2β1γ2s GABAA receptors respectively). SCS may bind allosterically to a novel site on GABAA receptor.


References

Thompson et al (2004) Salicylidene salicylhydrazide, a selective inhibitor of b1-containing GABAA receptors. Br.J.Pharmacol. 142 97.

Physical State :
Solid
Solubility :
Soluble to 50 mM in DMSO
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5371104
SMILES :
C1=CC=C(C(=C1)C(=O)NN/C=C\\2/C=CC=CC2=O)O

Download SDS (MSDS)

Certificate of Analysis

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