Salicylic acidCAS: 69-72-7
MF: C7H6O3
MW: 138.12
An antiinflammatory inhibitor of cyclooxygenase activity.

Salicylic acid (CAS 69-72-7)

Salicylic acid | CAS 69-72-7 is rated 5.0 out of 5 by 1.
  • y_2019, m_12, d_12, h_24
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.3
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_203374, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 80ms
  • REVIEWS, PRODUCT
5
1
4
0
3
0
2
0
1
0
Synonym: 2-hydroxybenzoic acid
Application: An antiinflammatory inhibitor of cyclooxygenase activity
CAS Number: 69-72-7
Purity: ≥99%
Molecular Weight: 138.12
Molecular Formula: C7H6O3
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Salicylic acid is a natural product extract from Willow bark, well known as an antiinflammatory and antinociceptive agent and a close structural relative to acetylsalicylic acid (aspirin). Salicylic acid is a ubiquitous plant hormone with many regulatory functions involved in local disease resistance mechanisms and systemic acquired resistance. The antiinflammatory and antinociceptive effects produced by Salicylic acid and its derivatives in animals are due to inhibition of COX-1 and COX-2 (cyclooxygenase) enzyme activity and suppression of prostaglandin biosynthesis. Salicylic acid is also of interest as a starting material for the organic synthesis of more elaborate COX suppressors and other chemical structures.


References

1. Delaney, T.P., et al. 1994. Science. 266: 1247-1250. PMID: 17810266
2. Steen, K.H., et al. 1996. Pain. 64: 71-82. PMID: 8867248
3. Mitchell, J.A., et al. 1997. Mol. Pharmacol. 51: 907-912. PMID: 9187256
4. Vane, J.R. and Botting, R.M. 1998. Am. J. Med. 104: 2S-21S. PMID: 9572314
5. Vlot, A.C., et al. 2009. Annu Rev Phytopathol. 47: 177-206. PMID: 19400653

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in water (1.8 g/L)
Storage :
Store at room temperature
Melting Point :
158-161° C (lit.)
Boiling Point :
211° C (lit.)
Density :
1.44 g/cm3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
VO0525000
PubChem CID :
338
Merck Index :
14,8332
EC Number :
200-712-3
Beilstein Registry :
774890
SMILES :
C1=CC=C(C(=C1)C(=O)O)O

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Salicylic acid  Product Citations

See how others have used Salicylic acid. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 21348489  Mironov, GG. et al. 2011. Analytical chemistry. 83: 2364-70.

Citations 1 to 1 of 1 total

Is this salicylic acid USP grade?

Asked by: specialty
Thank you for your question. No, our chemicals are research grade. We can not provide USP grade material.
Answered by: Tech Service
Date published: 2019-11-15
  • y_2019, m_12, d_12, h_24CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.3
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_203374, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 91ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Vlot et al Vlot et al. (PubMed ID 19400653) found that Salicylic acid mediates defense signaling in plants. -SCBT Publication Review
Date published: 2015-03-10
  • y_2019, m_12, d_12, h_24
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.3
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_203374, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 3ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.