Safinamide mesylate CAS: 202825-46-5
MF: C17H19FN2O2•CH4O3S
MW: 398.45
A potent and selective MAO-B inhibitor.

Safinamide mesylate (CAS 202825-46-5)

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Alternate Names: (S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide; (S)-2-[[4-[(3-Fluorobenzyl)oxy]benzyl]amino]
Application: Safinamide mesylate is a potent and selective MAO-B inhibitor
CAS Number: 202825-46-5
Purity: ≥98%
Molecular Weight: 398.45
Molecular Formula: C17H19FN2O2•CH4O3S
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Safinamide is a dopamine reuptake inhibitor by being a highly selective inhibitor of MAO-B (IC50 = 98 nM. Additionally, this compound has a high affinity for Na+ channels (IC50 = 8 μM.


References

PMID: 20707760 PMID: 9580576

Appearance :
white to tan powder
Physical State :
Solid
Solubility :
Soluble in water (≥ 15 mg/ml).
Storage :
Store at 4° C
Optical Activity :
α20D +11.75°±2.25°, c = 1 in 95% acetic acid
IC50 :
MAO-B: IC50 = 98 nM; Na+ channels: IC50 = 8 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
Transport :
UN 2811, Class 6.1, Packing group III
PubChem CID :
MDL Number :
MFCD15145475
SMILES :
C[[email protected]](C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F.CS(=O)(=O)O

Download SDS (MSDS)

Certificate of Analysis

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