S-Hexylglutathione (CAS 24425-56-7)
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S-Hexylglutathione functions as a potent antioxidant in experimental applications. It acts by scavenging free radicals and reactive oxygen species, thereby protecting cells and tissues from oxidative damage. S-Hexylglutathione′s mechanism of action involves the donation of electrons to neutralize harmful free radicals, preventing oxidative stress-induced cellular damage. S-Hexylglutathione also plays a role in detoxification processes within cells, aiding in the elimination of harmful substances and metabolic byproducts. At the molecular level, S-Hexylglutathione interacts with enzymes involved in redox reactions, enhancing their activity and contributing to the cellular antioxidant defense system. Its ability to modulate cellular redox balance may be useful for studying oxidative stress-related mechanisms in various experimental models.
S-Hexylglutathione (CAS 24425-56-7) References
- Characterization and cloning of avian-hepatic glutathione S-transferases. | Hsieh, CH., et al. 1999. Biochem J. 343 Pt 1: 87-93. PMID: 10493915
- Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione. | Ortiz-Salmerón, E., et al. 2003. J Biol Chem. 278: 46938-48. PMID: 12937169
- Identification of Tyr115 labeled by S-(4-bromo-2,3-dioxobutyl)glutathione in the hydrophobic substrate binding site of glutathione S-transferase, isoenzyme 3-3. | Katusz, RM., et al. 1992. Arch Biochem Biophys. 298: 667-77. PMID: 1416995
- Three-dimensional structure of class pi glutathione S-transferase from human placenta in complex with S-hexylglutathione at 2.8 A resolution. | Reinemer, P., et al. 1992. J Mol Biol. 227: 214-26. PMID: 1522586
- Plasmodium falciparum glutathione S-transferase--structural and mechanistic studies on ligand binding and enzyme inhibition. | Hiller, N., et al. 2006. Protein Sci. 15: 281-9. PMID: 16385005
- S-(4-Bromo-2,3-dioxobutyl)glutathione: a new affinity label for the 4-4 isoenzyme of rat liver glutathione S-transferase. | Katusz, RM. and Colman, RF. 1991. Biochemistry. 30: 11230-8. PMID: 1958660
- Characterization of glutathione S-transferases from day-old chick livers. | Chang, LH., et al. 1990. Biochemistry. 29: 744-50. PMID: 2337594
- Glutathione disulfide-stimulated Mg2+-ATPase of human erythrocyte membranes. | Kondo, T., et al. 1987. Proc Natl Acad Sci U S A. 84: 7373-7. PMID: 2959960
- Purification and partial characterization of the glutathione S-transferase of rat erythrocytes. | Dirr, HW. and Schabort, JC. 1988. Biochim Biophys Acta. 957: 173-7. PMID: 3191136
- Rat kidney glutathione S-transferase 1 subunits have C-terminal truncations. | Yeh, H., et al. 1996. Biochem J. 314 (Pt 3): 1017-25. PMID: 8615753
- Effect of glutathione, glutathione sulphonate and S-hexylglutathione on the conformational stability of class pi glutathione S-transferase. | Erhardt, J. and Dirr, H. 1996. FEBS Lett. 391: 313-6. PMID: 8764997
- Characterization of S-hexylglutathione-binding proteins of human hepatocellular carcinoma: separation of enoyl-CoA isomerase from an Alpha class glutathione transferase form. | Kajihara-Kano, H., et al. 1997. Biochem J. 328 (Pt 2): 473-8. PMID: 9371703
- Macrophage migration inhibitory factor interactions with glutathione and S-hexylglutathione. | Swope, MD., et al. 1998. J Biol Chem. 273: 14877-84. PMID: 9614090
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
S-Hexylglutathione, 25 mg | sc-394308 | 25 mg | $62.00 | |||
S-Hexylglutathione, 100 mg | sc-394308A | 100 mg | $114.00 |