Date published: 2025-10-1

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(S)-Bromoenol lactone-d7

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Molecular Weight:
324.2
Molecular Formula:
C16H6D7BrO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(S)-Bromoenol lactone-d7 is a chemically synthesized derivative of (S)-bromoenol lactone, distinguished by the substitution of hydrogen atoms with seven deuterium atoms, a form of hydrogen that contains one additional neutron. This modification increases the molecular mass and alters the vibrational modes of the molecule, which are pivotal in certain types of spectroscopic analyses, such as NMR (nuclear magnetic resonance). (S)-Bromoenol lactone-d7 retains the pharmacophoric elements of its parent compound, including the bromine atom and the lactone ring, which are crucial for its activity in biochemical assays. In research, this compound is particularly useful for probing the stereochemical aspects of enzymatic reactions involving esterases and lipases, enzymes that cleave ester bonds in fats and other substrates. The (S)-enantiomer specificity allows researchers to discern the enantioselective preferences of these enzymes, contributing to a deeper understanding of their catalytic mechanisms. Additionally, the deuterium labeling facilitates the tracking of metabolic and chemical degradation pathways in complex biological systems, helping to explain minute details of molecular interactions and transformations. This makes (S)-Bromoenol lactone-d7 a valuable tool in fields such as enzymology, metabolic engineering, and the study of lipid dynamics within biological membranes.


(S)-Bromoenol lactone-d7 References

  1. Regulation and inhibition of phospholipase A2.  |  Balsinde, J., et al. 1999. Annu Rev Pharmacol Toxicol. 39: 175-89. PMID: 10331081
  2. Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammalian iPLA2s.  |  Jenkins, CM., et al. 2002. J Biol Chem. 277: 32807-14. PMID: 12089145

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(S)-Bromoenol lactone-d7, 100 µg

sc-344999
100 µg
$36.00

(S)-Bromoenol lactone-d7, 500 µg

sc-344999A
500 µg
$163.00