Date published: 2026-3-22

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(S)-(+)-Ascochin (CAS 935699-58-4)

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Application:
(S)-(+)-Ascochin is Antibiotic and Antifungal
CAS Number:
935699-58-4
Purity:
≥98%
Molecular Weight:
234.2
Molecular Formula:
C12H10O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(S)-(+)-Ascochin, a chiral fungal metabolite characterized by its unique bicyclic lactone and quinone structures, plays a significant role in scientific research due to its involvement in redox processes within cells. This compound, specifically in its (S)-enantiomer form, acts primarily as an electron acceptor, influencing the balance of reactive oxygen species (ROS) and thereby impacting cellular oxidative stress mechanisms. The quinone component of (S)-(+)-Ascochin is crucial for these interactions, as it can both trigger and mitigate oxidative stress depending on specific cellular conditions and the presence of other environmental factors. This dual role makes it an invaluable tool for studying cellular defense mechanisms against oxidative damage and understanding how cells adapt to oxidative stress. In research contexts, (S)-(+)-Ascochin is used to explore the biochemical pathways related to ROS management, providing insights into both the natural roles of fungal secondary metabolites in ecological systems and their potential applications in biotechnology. Through these studies, (S)-(+)-Ascochin not only enhances our understanding of fungal biology but also aids in the development of new strategies for managing oxidative stress in various biological and environmental systems.


(S)-(+)-Ascochin (CAS 935699-58-4) References

  1. Electronic CD of benzene and other aromatic chromophores for determination of absolute configuration[J].  |  Kurtan T, Antus S, Pescitelli G. 2012,. Comprehensive chiroptical spectroscopy: applications in stereochemical analysis of synthetic compounds, natural products, and biomolecules,. 2:: 73-114.
  2. Lycopodiellactone, an unusual δ-lactone-isochromanone from a Hawaiian plant-associated fungus Paraphaeosphaeria neglecta FT462[J].  |  Li C, Yang B, Fenstemacher R,. 2015,. Tetrahedron Letters,. 56(13):: 1724-1727.
  3. Sphaerialactonam, a γ-lactam–isochromanone from the Hawaiian endophytic fungus Paraphaeosphaeria sp. FT462[J].  |  Huang P, Li C, Sarotti A M,. 2017,. Tetrahedron Letters,. 58(13):: 1330-1333.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(S)-(+)-Ascochin, 1 mg

sc-364133
1 mg
$160.00

(S)-(+)-Ascochin, 5 mg

sc-364133A
5 mg
$510.00