(S)-3-Hydroxyphenylglycine is an agonist at group I metabotropic glutamate receptors (mGluR) having no effect at mGluR-2 or mGluR-4.
1. Birse et al (1993) Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience 52 481. 2. Hayashi et al (1994) Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J.Neurosci. 14 3370.
Soluble in water (50 mM), phosphate buffered saline (50 mM), 1eq NaOH (100 mM), and 1eq HCl (100 mM).
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