Anti-RXRα Antibody (H-10) is a mouse monoclonal IgG1 κ RXRα antibody, cited in 7 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 2-29 at the N-terminus of RXRα of human origin
Anti-RXR alpha Antibody (H-10) is recommended for detection of RXRα of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-RXR alpha Antibody (H-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
TransCruz reagent for Gel Supershift and ChIP applications (sc-515929 X, 200 µg/0.1 ml)
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of RXRα (H-10): sc-515929.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for RXRα Antibody (H-10) for WB and IHC(P) applications. These reagents are now offered in bundles with RXRα Antibody (H-10) (see ordering information below).
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Labware ships FedEx Ground free of charge to the contiguous US
RXRα Antibody (H-10) is a high quality monoclonal RXR alpha antibody (also designated RXRA antibody, retinoid X receptor alpha antibody, or NR2B1 antibody) suitable for the detection of the RXR alpha protein of mouse, rat and human origin. RXRα Antibody (H-10) is available as both the non-conjugated anti-RXR alpha antibody form, as well as multiple conjugated forms of anti-RXR alpha antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARα, RARβ and RARγ, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRα, RXRβ and RXRγ, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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