Rugulosin (+ form)An intense yellow pigment produced by Penicillium and Aspergillus

Rugulosin (+ form) (CAS 23537-16-8)

Rugulosin (+ form) | CAS 23537-16-8 is rated 5.0 out of 5 by 1.
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Synonym: Radicalisin
Application: An intense yellow pigment produced by Penicillium and Aspergillus
CAS Number: 23537-16-8
Purity: >98%
Molecular Weight: 542.5
Molecular Formula: C30H22O10
* Refer to Certificate of Analysis for lot specific data (including water content).
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Rugulosin is an intense yellow pigment produced by some fungal species of Penicillium, Aspergillus and the fungal symbiotants of some lichens. Rugulosin shows antibacterial and insecticidal activity and has found application as a bioinsecticide, notably as the active secondary metabolite in endophytic fungi of seedlings. Rugulosin (+ form) is an inhibitor of RNA Polymerase and RNase.


References

1. Breen, J., et al. 1955. Biochem. J. 60: 618-626. PMID: 13249956
2. Miller, J.D., et al. 2008. J. Chem. Ecol. 34: 362-368. PMID: 18266038
3. Watts P., et al. 2003. Mycol. Res. 107: 581-586. PMID: 12884955

Physical State :
Solid
Derived From :
Penicillium
Solubility :
Soluble in water (limited), ethanol, methanol, DMSO, and DMF.
Storage :
Store at -20° C
Boiling Point :
980.03° C at 760 mmHg (Predicted)
Density :
1.88 g/cm3 (Predicted)
Refractive Index :
n20D 1.87 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
VM1610000
PubChem CID :
62769
SMILES :
CC1=CC(=C2C(=C1)C(=O)C34C5C6C(C3C(=O)C7=C(C8=C(C=C(C=C8C(=O)C67C(C5O)C(=O)C4=C2O)C)O)O)O)O

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Certificate of Analysis

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Rugulosin (+ form)  Product Citations

See how others have used Rugulosin (+ form). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 7218376  Ueno, Y. et al. 1980. J Toxicol Sci. 5: 295-302.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Ueno et al Ueno et al. (PubMed ID 7218376 ) found that when subcutaneously injected into rats, Rugulosin caused an elevation of serum transaminase activity and liver cell necrosis, revealing Rugulosin s nature as a slow-acting hepatotoxin. -SCBT Publication Review
Date published: 2015-07-10
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