(RS)-3-HydroxyphenylglycineAn agonist at PI-linked metabotropic glutamate receptors

(RS)-3-Hydroxyphenylglycine (CAS 31932-87-3)

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Synonym: (RS)-3H-PG
Application: An agonist at PI-linked metabotropic glutamate receptors
CAS Number: 31932-87-3
Molecular Weight: 167.16
Molecular Formula: C8H9NO3
* Refer to Certificate of Analysis for lot specific data (including water content).
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(RS)-3-Hydroxyphenylglycine is an agonist at PI-linked mGluR (metabotropic glutamate receptors).


References

Birse et al (1993) Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience 52 481.

Physical State :
Solid
Solubility :
Soluble in 1eq. NaOH (100 mM).
Storage :
Desiccate at room temperature
Melting Point :
238.81° C (Predicted)
Boiling Point :
~382.6° C at 760 mmHg (Predicted)
Density :
~1.4 g/cm3 (Predicted)
Refractive Index :
n20D 1.63 (Predicted)
Ki Data :
mGluR-5: Ki= 14 µM; mGluR-1: Ki= 1000 µM; mGluR-2: Ki= >1000 µM; mGluR-4: Ki= >1000 µM
pK Values :
pKa: 1.85 (Predicted), pKb: 10.36 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
1217
MDL Number :
MFCD00673854
SMILES :
C1=CC(=CC(=C1)O)C(C(=O)O)N

Download SDS (MSDS)

Certificate of Analysis

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