Rp-8-pCPT-cyclic GMPS Sodium is a potent and selective inhibitor of cGMP-dependent protein kinase (PKG) 1α, 1β and type II. The compound is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Rp-8-pCPT-cyclic GMPS Sodium is significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS.
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