Rp-8-Br-PET-cyclic GMPS, Sodium Salt is a metabolically-stable, competitive inhibitor of cGKI (cGKI α and β). This compound blocks cGMP-gated retinal type ion channels (IC50 = 25 μM) and the activation of purified PKA type II (Ki = 10 μM). Rp-8-Br-PET-cyclic GMPS, Sodium Salt is more lipophilic and cell-permeable than Rp-8-pCPT-cGMPS . Note: 1 μmol = 0.56 mg. Rp-8-Br-PET-cyclic GMPS, Sodium Salt is an inhibitor of cGKII.
Soluble in water (15 mg/ml at 60° C), and DMSO (40 mM).
Store at -20° C
240-300° C (lit.)
cGMP-gated retinal type ion channels: IC50 = 25 µM; PKA2: IC50 = 10 µM
protein kinase G types 1α: Ki= 30 nM; protein kinase G types 1β: Ki= 30 nM; PKA2: Ki= 10 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.Hide
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.