RIM-1 is a fluorescent probe for protein kinase C (PKC). The compound binds to the catalytic site of all PKC enzymes. RIM-1 provides a rapid and simple means for visualizing the distribution of PKC in cells.
1. Chen, C S., et al., 1993. New fluorescent probes for protein kinase C. Synthesis, characterization, and application. The Journal of biological chemistry. 268(21): 15812-22. PMID: 8340406
2. Gallicano, G I., et al., 1997. Activation of protein kinase C after fertilization is required for remodeling the mouse egg into the zygote. Molecular reproduction and development. 46(4): 587-601. PMID: 9094105