RIM-1 MF: C51H50N6O8S2
MW: 939.1
A fluorescent probe for PKC.

RIM-1

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Alternate Names: Rhodamine-conjugated Bisindolylmaleimide Inhibitor
Application: RIM-1 is a fluorescent probe for PKC
Molecular Weight: 939.1
Molecular Formula: C51H50N6O8S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

RIM-1 is a fluorescent probe for protein kinase C (PKC). The compound binds to the catalytic site of all PKC enzymes. RIM-1 provides a rapid and simple means for visualizing the distribution of PKC in cells.


References

1. Chen, C S., et al., 1993. New fluorescent probes for protein kinase C. Synthesis, characterization, and application. The Journal of biological chemistry. 268(21): 15812-22. PMID: 8340406
2. Gallicano, G I., et al., 1997. Activation of protein kinase C after fertilization is required for remodeling the mouse egg into the zygote. Molecular reproduction and development. 46(4): 587-601. PMID: 9094105

Physical State :
Solid
Solubility :
Soluble in DMSO or Methanol
Storage :
Store at -20° C
Fluoresence :
λex 562 ± 3 nm, λem 581 ± 4 nm in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
3081320
SMILES :
CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](CC)CC)C=C3O2)C4=C(C=C(C=C4)S(=O)(=O)NCCCN5C=C(C6=CC=CC=C65)C7=C(C(=O)NC7=O)C8=CN(C9=CC=CC=C98)C)S(=O)(=O)[O-]

Download SDS (MSDS)

Certificate of Analysis

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