Resiniferonol 9,13,14-ortho-phenylacetateA derivative of resiniferatoxin not active as a capsaicin analog

Resiniferonol 9,13,14-ortho-phenylacetate (CAS 57852-42-3)

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Application: A derivative of resiniferatoxin not active as a capsaicin analog
CAS Number: 57852-42-3
Molecular Weight: 464.55
Molecular Formula: C28H32O6
* Refer to Certificate of Analysis for lot specific data (including water content).
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Resiniferonol 9,13,14-ortho-phenylacetate is a 20-Deacylated derivative of resiniferatoxin and tinyatoxin. Not active as a capsaicin analog. Resiniferonol 9,13,14-ortho-phenylacetate binds with high potency to PKC (protein kinase C), activating the enzyme. Useful as starting material for synthesis of resiniferatoxin analogs.


References

1. Frey, M.R., et al. 2004. Biochem. Pharmacol. 67:1873-1886. PMID: 15130764

Physical State :
Solid
Solubility :
Soluble in DMSO, and 100% ethanol.
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
21058718
SMILES :
CC1CC2(C3C4C1(C5C=C(C(=O)C5(CC(=C4)CO)O)C)OC(O3)(O2)CC6=CC=CC=C6)C(=C)C

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Certificate of Analysis

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Resiniferonol 9,13,14-ortho-phenylacetate  Product Citations

See how others have used Resiniferonol 9,13,14-ortho-phenylacetate. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26431317  Glover, KP. et al. 2015. PLoS ONE. 10: e0139850.

Citations 1 to 1 of 1 total
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