RegadenosonA selective A2A adenosine receptor agonist in myocardial imaging

Regadenoson (CAS 313348-27-5)

Regadenoson | CAS 313348-27-5 is rated 5.0 out of 5 by 1.
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Synonym: 2-[4-[(Methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine
Application: A selective A2A adenosine receptor agonist in myocardial imaging
CAS Number: 313348-27-5
Purity: ≥98%
Molecular Weight: 390.35
Molecular Formula: C15H18N8O5
* Refer to Certificate of Analysis for lot specific data (including water content).
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Regadenoson is a selective Adenosine A2A-R (A2A adenosine receptor) agonist in myocardial imaging.


References

Palle, V.P., et al.: J. A. Drug Dev. Res., 50, 64 (2000),

Physical State :
Solid
Solubility :
Soluble in DMSO, and methanol.
Storage :
Store at -20° C
Melting Point :
194-196° C
Boiling Point :
744.10° C (Predicted)
Density :
~2.0 g/cm3 (Predicted)
Refractive Index :
n20D 1.90 (Predicted)
Ki Data :
Adenosine A2A-R: Ki= 290 nM (human); Adenosine A2A-R: Ki= 290 nM (rat); Adenosine A1-R: Ki>16.46 mM (human)
pK Values :
pKa: 13.07, pKb: 1.32
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
219024
MDL Number :
MFCD09832544
SMILES :
CNC(=O)C1=CN(N=C1)C2=NC3=C(C(=N2)N)N=CN3[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O

Download SDS (MSDS)

Certificate of Analysis

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What's uv peak and Landa max for regadenoson and what solvent use to measure it and what conctration

Asked by: Ali Mazen 1991
Thank you for your question. Unfortunately we do not test uv peak and Landa max, so we are unable to provide that information. Here is a link to a sample CoA for this product: http://datasheets.scbt.com/coa/coa.php?sc=sc-222245&lot=J1018
Answered by: Tech Service
Date published: 2019-10-28

What is the shipping temperature of this product?

Asked by: hawkeye11
This chemical, Regadenoson (CAS 313348-27-5), is shipped ambient.
Answered by: Chemical Support 1
Date published: 2019-01-25
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Rated 5 out of 5 by from Field Field, JJ. et al. (PubMed 23377438) reported that the adenosine A2A receptor agonist Regadenoson decreased activation of iNKT cells induced by sickle cell vaso-occlusion. -SCBT Publication Review
Date published: 2015-01-06
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