Rauwolscine dot HCl CAS: 6211-32-1
MF: C21H26N2O3 HCl
MW: 390.9
A standard α-2-adrenergic (AR) antagonist.

Rauwolscine • HCl (CAS 6211-32-1)

Rauwolscine andbull HCl | CAS 6211-32-1 is rated 5.0 out of 5 by 1.
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Alternate Names: α-Yohimbine hydrochloride
Application: Rauwolscine • HCl is a standard α-2-adrenergic (AR) antagonist
CAS Number: 6211-32-1
Purity: ≥98%
Molecular Weight: 390.9
Molecular Formula: C21H26N2O3 HCl
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Rauwolscine • HCl is a standard α2-adrenergic antagonist (Ki values are 3.5, 4.6 , and 0.6 nM at cloned human α2A-AR, , α2B-AR, and α2C-AR adrenoceptors respectively). Also exhibits partial agonist characteristics at 5-HT1A receptors.


References

1. Hieble, J.P., et al. 1995. J. Med. Chem. 38: 3415-3444. PMID: 7658428
2. Rump, L.C., et al. 1995. J. Cardiovasc. Pharmacol. 26: 462-470. PMID: 8583789

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in ethanol (5 mM), water (5 mM), and DMSO (25 mM).
Storage :
Store at room temperature
Melting Point :
288-290° C (dec.)
Boiling Point :
543° C at 760 mmHg (Predicted)
Ki Data :
α2A-adrenoceptor: Ki= 3.5 nM; α2B-adrenoceptor: Ki= 4.6 nM; α2C-adrenoceptor: Ki= 0.6 nM
pK Values :
pKb: 8.44 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
ZG1035000
PubChem CID :
MDL Number :
MFCD06668052
EC Number :
228-279-6
SMILES :

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Rauwolscine Hcl Rauwolscine Hcl, is reported in many articles as an 2-adrenergic receptor antagonist and a stereo isomer of Yohimbine. -SCBT Publication Review
Date published: 2015-04-03
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