Rauwolscine dot HClA standard α-2-adrenergic (AR) antagonist

Rauwolscine • HCl (CAS 6211-32-1)

Rauwolscine andbull HCl | CAS 6211-32-1 is rated 5.0 out of 5 by 1.
  • y_2019, m_11, d_12, h_16
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.1
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_200151, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 163ms
  • REVIEWS, PRODUCT
5
1
4
0
3
0
2
0
1
0
Synonym: α-Yohimbine hydrochloride
Application: A standard α-2-adrenergic (AR) antagonist
CAS Number: 6211-32-1
Purity: ≥98%
Molecular Weight: 390.9
Molecular Formula: C21H26N2O3 HCl
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Rauwolscine • HCl is a standard α2-adrenergic antagonist (Ki values are 3.5, 4.6 , and 0.6 nM at cloned human α2A-AR, , α2B-AR, and α2C-AR adrenoceptors respectively). Also exhibits partial agonist characteristics at 5-HT1A receptors.


References

1. Hieble, J.P., et al. 1995. J. Med. Chem. 38: 3415-3444. PMID: 7658428
2. Rump, L.C., et al. 1995. J. Cardiovasc. Pharmacol. 26: 462-470. PMID: 8583789

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in ethanol (5 mM), water (5 mM), and DMSO (25 mM).
Storage :
Store at room temperature
Melting Point :
288-290° C (dec.)
Boiling Point :
543° C at 760 mmHg (Predicted)
Ki Data :
α2A-adrenoceptor: Ki= 3.5 nM; α2B-adrenoceptor: Ki= 4.6 nM; α2C-adrenoceptor: Ki= 0.6 nM
pK Values :
pKb: 8.44 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
ZG1035000
PubChem CID :
197067
MDL Number :
MFCD06668052
EC Number :
228-279-6
SMILES :
COC(=O)[C@@H]1[C@H](CC[C@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 64ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Rauwolscine Hcl Rauwolscine Hcl, is reported in many articles as an 2-adrenergic receptor antagonist and a stereo isomer of Yohimbine. -SCBT Publication Review
Date published: 2015-04-03
  • y_2019, m_11, d_12, h_16
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.1
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_200151, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 72ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.