Rapamycin-d3 (contains d0)A labeled Rapamycin

Rapamycin-d3 (contains d0) (CAS 53123-88-9 unlabeled)

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Synonym: (-)-Rapamycin-d3; AY 22989-d3; Antibiotic AY 22989-d3
Application: A labeled Rapamycin
CAS Number: 53123-88-9 unlabeled
Purity: ≥65%
Molecular Weight: 917.19
Molecular Formula: C51H76D3NO13
* Refer to Certificate of Analysis for lot specific data (including water content).
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Rapamycin-d3 (contains d0) is a labeled Rapamycin. It is also a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Its name was derived from the native word for Easter Island, Rapa'Nui. It can be used as an immunosuppressant and antirestenotic. This compound contains approximately 2% d0.


References

Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977) Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993) Kahan, B.D., et al.: Lancet, 356, 194 (2000) Holmes, D.R., et al.: Circulation, 109, 634 (2004)

Physical State :
Solid
Solubility :
Soluble in Dichloromethane and Methanol
Storage :
Store at -20° C
Melting Point :
101-103° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
71751978
SMILES :
[2H]C([2H])([2H])O[C@@H]\1C[C@@H]2CC[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H](CC(=O)[C@@H](/C=C(/[C@H]([C@H](C(=O)[C@@H](C[C@@H](/C=C/C=C/C=C1\C)C)C)OC)O)\C)C)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)O)C

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Certificate of Analysis

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Rapamycin-d3 (contains d0)  Product Citations

See how others have used Rapamycin-d3 (contains d0). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 22322402  McMillin, GA. et al. 2012. Ther Drug Monit. 34: 222-6.

Citations 1 to 1 of 1 total
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