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Rapamycin-d3 (contains d0) is a labeled Rapamycin. It is also a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Its name was derived from the native word for Easter Island, Rapa'Nui. It can be used as an immunosuppressant and antirestenotic. This compound contains approximately 2% d0.
Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977) Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993) Kahan, B.D., et al.: Lancet, 356, 194 (2000) Holmes, D.R., et al.: Circulation, 109, 634 (2004)
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