Anti-Rab 5 Antibody (D-11) is a mouse monoclonal IgG2b κ Rab 5 antibody, cited in 89 publications, provided at 200 µg/ml
raised against amino acids 1-215 representing full length Rab 5AA of human origin
Anti-Rab 5 Antibody (D-11) is recommended for detection of Rab 5A, 5B and 5C; partially cross reactive with other Rab family members of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine
Anti-Rab 5 Antibody (D-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Rab 5 (D-11): sc-46692.
m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Rab 5 Antibody (D-11) for WB and IHC(P) applications. These reagents are now offered in bundles with Rab 5 Antibody (D-11) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Rab 5 Antibody (D-11) is a high quality monoclonal Rab 5 antibody (also designated RAB5A antibody, RAB5B antibody, RAB5C antibody, or RAB5 member RAS oncogene family antibody) suitable for the detection of the Rab 5 protein of mouse, rat and human origin. Rab 5 Antibody (D-11) is available as both the non-conjugated anti-Rab 5 antibody form, as well as multiple conjugated forms of anti-Rab 5 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the Sec4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. At least eight members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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