(R)-(+)-m-Nitrobiphenyline oxalate is an α2C-AR (adrenoceptor) agonist that potently inhibits cAMP accumulation in CHO cells (EC50 = 38 nM).It behaves as an antagonist at α2A-AR and α2B-AR (pKb = 7.11 and 6.07 respectively).
1. Crassous, Pierre-Antoine., et al., 2007. Alpha2-adrenoreceptors profile modulation. 3.1 (R)-(+)-m-nitrobiphenyline, a new efficient and alpha2C-subtype selective agonist. Journal of medicinal chemistry. 50(16): 3964-8. PMID: 17630725