Date published: 2025-12-7

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(R)-Bromoenol lactone-d7 (CAS 478288-90-3 (unlabeled))

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Alternate Names:
(R)-BEL-d7
CAS Number:
478288-90-3 (unlabeled)
Molecular Weight:
324.2
Molecular Formula:
C16H6D7BrO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(R)-Bromoenol lactone-d7 is a deuterated analogue of (R)-bromoenol lactone, a specialized chemical primarily utilized for mechanistic studies in enzyme chemistry and lipid metabolism. This compound is characterized by its structure containing a bromine atom and a lactone ring, with the presence of seven deuterium atoms enhancing its stability and making it a preferred choice for specific isotopic labeling experiments. In research, (R)-Bromoenol lactone-d7 is employed to investigate the catalytic mechanisms of various enzymes, particularly those involved in lipid processing, such as phospholipases. The deuterium atoms are critical as they allow for the tracing and analysis of reaction pathways through techniques like NMR spectroscopy, providing clearer insights into enzyme-substrate interactions and the dynamics of enzyme function without the interference that might occur with non-labeled compounds. Additionally, this compound is useful in the study of kinetic isotope effects where differences in reaction rates between hydrogen and deuterium atoms can explain details of chemical transformations at the molecular level. This makes (R)-Bromoenol lactone-d7 a valuable tool for researchers aiming to dissect complex biochemical processes, especially those relevant to lipid biochemistry, without the confounding effects often associated with similar non-deuterated compounds.


(R)-Bromoenol lactone-d7 (CAS 478288-90-3 (unlabeled)) References

  1. Regulation and inhibition of phospholipase A2.  |  Balsinde, J., et al. 1999. Annu Rev Pharmacol Toxicol. 39: 175-89. PMID: 10331081
  2. Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammalian iPLA2s.  |  Jenkins, CM., et al. 2002. J Biol Chem. 277: 32807-14. PMID: 12089145

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(R)-Bromoenol lactone-d7, 100 µg

sc-344988
100 µg
$44.00

(R)-Bromoenol lactone-d7, 500 µg

sc-344988A
500 µg
$262.00