(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazineAn inhibitor with antitumor activity

(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine (CAS 109838-85-9)

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Application: An inhibitor with antitumor activity
CAS Number: 109838-85-9
Molecular Weight: 184.24
Molecular Formula: C9H16N2O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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(R)-2-Isopropyl-3,6-dimethoxy-2,5-dihydropyrazine is an inhibitor with antitumor activity.


References

1. de Ruijter, Annemieke J M., et al., 2003. Histone deacetylases (HDACs): characterization of the classical HDAC family. The Biochemical journal. 370(Pt 3): 737-49. PMID: 12429021
2. Plumb, Jane A., et al., 2003. Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101. Molecular cancer therapeutics. 2(8): 721-8. PMID: 12939461
3. Maiso, Patricia., et al., 2006. The histone deacetylase inhibitor LBH589 is a potent antimyeloma agent that overcomes drug resistance. Cancer research. 66(11): 5781-9. PMID: 16740717
4. Dey, Pranab., et al., 2006. Chromatin remodeling, cancer and chemotherapy. Current medicinal chemistry. 13(24): 2909-19. PMID: 17073637
5. Paris, Marielle., et al., 2008. Histone deacetylase inhibitors: from bench to clinic. Journal of medicinal chemistry. 51(6): 1505-29. PMID: 18247554

Solubility :
Soluble in Chloroform and Ethanol
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
736066
SMILES :
CC(C)[C@@H]1C(=NCC(=N1)OC)OC

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Certificate of Analysis

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