Quinidine sulfate dihydrateA Na+ channel blocker

Quinidine sulfate dihydrate (CAS 6591-63-5)

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Application: A Na+ channel blocker
CAS Number: 6591-63-5
Molecular Weight: 782.9
Molecular Formula: (C20H24N2O2)2•H2SO42H2O
* Refer to Certificate of Analysis for lot specific data (including water content).
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Quinidine sulfate dihydrate is a diastereomer of quinine and a Na+ channel blocker. Also a class I antiarrhythmic drug.


References

1. Roden, D.M., et al. 1983. Pharmacol. Ther. 23: 179-191. PMID: 619980
2. Mason, J.W., et al. 1984. Ann. N.Y. Acad. Sci. 432: 162-17. PMID: 6395759
3. Salerno, D.M. 1992. Postgrad. Med. 92: 131-140. PMID: 1528812
4. Belhassen, B., et al. 2004. Circulation. 110: 1731-1737. PMID: 15381640

Physical State :
Solid
Solubility :
Soluble in chloroform, water (11 mg/ml at 20° C), alcohol, and ethanol (50 mg/ml).
Storage :
Store at 4° C
Melting Point :
212-214° C (lit.)(dec.)
Boiling Point :
992.5° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.64 (Predicted)
Optical Activity :
α20/D +275°±5°, c = 2 in 0.1mol/L HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
VA5605000
PubChem CID :
16219922
Merck Index :
14: 8060
MDL Number :
MFCD00149346
EC Number :
200-046-3
SMILES :
COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O.COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O.O.O.OS(=O)(=O)O

Download SDS (MSDS)

Certificate of Analysis

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