QUIN 2, Tetrapotassium SaltCAS: 73630-23-6
MF: C26H23N3O10 4K
MW: 693.9
A useful fluorescing calcium indicator.

QUIN 2, Tetrapotassium Salt (CAS 73630-23-6)

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Application: A useful fluorescing calcium indicator
CAS Number: 73630-23-6
Molecular Weight: 693.9
Molecular Formula: C26H23N3O10 4K
* Refer to Certificate of Analysis for lot specific data (including water content).
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QUIN 2, Tetrapotassium Salt has been demonstrated to be an indicator of Zn2+-protein complexes.The binding of Ca2+ to QUIN 2 leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield. TPEN (sc-200131) can be used in conjunction with QUIN 2 to reduce heavy-metal quenching of QUIN 2 fluorescence in cells. Spectral properties in the presence of low calcium concentrations (ex. 354 nm, em. 510 nm) differ from those during high calcium conditions (ex. 332 nm, em. 505 nm).


1. Komada, H., et al. 1989. Cell Struct. Funct. 14: 141. PMID: 2743418
2. Vijayaraghavan, S., et al. 1989. Cell Calcium 10: 241-253. PMID: 2776189
3. Arslan, P., et al. 1985. J. Biol. Chem. 260: 2719-2727. PMID: 3919006
4. Bryant, D.T. 1985. Biochem. J. 226: 613-616. PMID: 3994676
5. Grynkiewicz, G., et al. 1985. J. Biol. Chem. 260: 3440-3450. PMID: 3838314
6. Ashley R.H., et al. 1984. Biochem. J. 219: 149-158. PMID: 6326754
Tsien, R.Y., et al. 1982. J. Cell Biol. 94: 325-334. PMID: 6980885
Tsien, R.Y., et al. 1980. Biochemistry. 19: 2396-2404. PMID: 6770893

Physical State :
Solubility :
Soluble in water (10 mg/ml).
Storage :
Store at -20° C
Melting Point :
163.9-166.1° C
Boiling Point :
831.6° C at 760 mmHg (Predicted)
Fluoresence :
λex 332 nm, λem 493 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+; λex 332-354 nm, λem 505-510 nm
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 8042
MDL Number :
Beilstein Registry :

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Certificate of Analysis

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To whom it may concern, My name is Akio Kikuchi from Dojindo Molecular Technologies, Inc. I would like to request a quote of 3000 mg of QUIN 2, Tetrapotassium Salt (CAS 73630-23-6). Could you please also tell me the current stock of QUIN 2?

Asked by: Akio
Thank you very much for your message. Our Customer Service Department will contact you by email.
Answered by: Technical Support Europe
Date published: 2018-01-11
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