PuerarinA flavonoid derivative with potential antioxidant activity

Puerarin (CAS 3681-99-0)

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Synonym: 8-(β-D-Glucopyranosyl-7-hydroxy-3- (4-hydroxyphenyl)-4H-1-benzopyran-4-one
Application: A flavonoid derivative with potential antioxidant activity
CAS Number: 3681-99-0
Purity: ≥98%
Molecular Weight: 416.38
Molecular Formula: C21H20O9
* Refer to Certificate of Analysis for lot specific data (including water content).
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Puerarin is a flavonoid derivative from the traditional oriental medicine, Ge-gen. Purarin has potential antioxidant activity and impairs CYP catalyzed drug metabolism. A metabolite, calycosin, shows cytotoxic activity. Puerarin is an inhibitor of SR-2C (5-HT2C receptor) .


References

1. Kim, D.H., et al. 1998. J. Biol Pharm Bull. 21: 628-360. PMID: 9657051
2. Guerra, M.C., et al. 2000. Life Sci. 67: 2997-3006. PMID: 11133012

Appearance :
Powder
Physical State :
Solid
Derived From :
Kudzu root
Solubility :
Soluble in methanol, and DMSO.
Storage :
Store at 4° C
Melting Point :
187° C
pK Values :
pKa: 6.46
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
UO5216000
PubChem CID :
5281807
MDL Number :
MFCD00076007
Beilstein Registry :
64198
SMILES :
C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O

Download SDS (MSDS)

Certificate of Analysis

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