Date published: 2025-11-9

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PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt)

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Alternate Names:
Phosphatidylinositol-3,4,5-triphosphate C-18 (sodium salt)
Molecular Weight:
1215.00
Molecular Formula:
C47H82O22P44Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt) is a phosphoinositide that plays a crucial role in cellular signaling pathways. It acts as a second messenger, regulating various cellular processes such as cell growth, proliferation, and survival. TPtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) binds to specific proteins, such as Akt and PDK1, and facilitating their translocation to the cell membrane. Once bound, it activates these proteins, leading to the activation of downstream signaling cascades. PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt) recruits proteins to the cell membrane, where they participate in signaling events. PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt) interacts with various signaling molecules modulating cellular responses to extracellular stimuli.


PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt) References

  1. Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate.  |  Yang, X., et al. 1999. J Biol Chem. 274: 18973-80. PMID: 10383396
  2. Inositol phosphate biochemistry.  |  Majerus, PW. 1992. Annu Rev Biochem. 61: 225-50. PMID: 1323235
  3. Benign polypoid adenoma of the ampulla of vater. Treatment by double sphincteroplasty.  |  Archie, JP. and Murray, HM. 1978. Arch Surg. 113: 180-1. PMID: 626579
  4. Inositol trisphosphate and calcium signalling.  |  Berridge, MJ. 1993. Nature. 361: 315-25. PMID: 8381210
  5. Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains.  |  Pike, LJ. and Casey, L. 1996. J Biol Chem. 271: 26453-6. PMID: 8900109
  6. A target of phosphatidylinositol 3,4,5-trisphosphate with a zinc finger motif similar to that of the ADP-ribosylation-factor GTPase-activating protein and two pleckstrin homology domains.  |  Tanaka, K., et al. 1997. Eur J Biochem. 245: 512-9. PMID: 9151987

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt), 50 µg

sc-222206
50 µg
$142.00

PtdIns-(3,4,5)-P3 (1-stearoyl, 2-arachidonoyl) (sodium salt), 100 µg

sc-222206A
100 µg
$267.00