Prostaglandin F2α dimethyl amide is a weak prostaglandin F receptor (FP; PGF2Rα) antagonist. PGF2α dimethyl amide is able to inhibit the contractile effects of PGF2α in gerbil colon by 50% at a dose of 3.2 µg/ml.
1 Maddox, Y.T., Ramwell, P.T., Shiner, C.S., et al. Amide and l-amino derivatives of F prostaglandins as prostaglandin antagonists. Nature 273 549-552 (1978).
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