Propafenone HydrochlorideCAS: 34183-22-7
MF: C21H27NO3•HCl
MW: 377.91
A sodium channel protein inhibitor.

Propafenone Hydrochloride (CAS 34183-22-7)

Propafenone Hydrochloride | CAS 34183-22-7 is rated 4.0 out of 5 by 1.
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Application: A sodium channel protein inhibitor
CAS Number: 34183-22-7
Purity: ≥98%
Molecular Weight: 377.91
Molecular Formula: C21H27NO3•HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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Propafenone Hydrochloride is a sodium channel protein inhibitor. Propafenone Hydrochloride is an inhibitor of AR.


References

1. Muller-Peltzer, H., et al. 1983. Eur J Clin Pharmacol. 25:831-833. PMID: 6662183
2. Harder, D.R. and Belardinelli, L. 1980. Experientia. 36:1082-1083. PMID: 7418845

Physical State :
Solid
Solubility :
Soluble in methanol (50 mg/ml), water(slightly soluble in cold water), ethanol, acetone, and chloroform.
Storage :
Store at -20° C
Melting Point :
172-175° C
Boiling Point :
519.6° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.56 (Predicted)
IC50 :
Plasmodium falciparum: IC50 = 0.23 nM; β-2 adrenergic receptor: IC50 = 52 nM (human); SR-2B: IC50 = 92 nM (human); β-1 adrenergic receptor: IC50 = 354 nM (human); SR-2C: IC50 = 384 nM (human)
Ki Data :
β-2 adrenergic receptor: Ki= 36 nM (human); SR-2B: Ki= 58 nM (human); SR-2A: Ki= 187 nM (human); SR-2C: Ki= 201 nM (human); β-1 adrenergic receptor: Ki= 205 nM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
36708
Merck Index :
14: 7794
MDL Number :
MFCD00079243
EC Number :
251-867-9
SMILES :
CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O.Cl

Download SDS (MSDS)

Certificate of Analysis

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Rated 4 out of 5 by from Works good Works good!
Date published: 2015-09-03
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