Prochlorperazine, dimaleateA D2 dopamine receptor antagonist

Prochlorperazine, dimaleate (CAS 84-02-6)

Prochlorperazine, dimaleate | CAS 84-02-6 is rated 5.0 out of 5 by 1.
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Synonym: 2-Chloro-10-[3[(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine dimaleate
Application: A D2 dopamine receptor antagonist
CAS Number: 84-02-6
Purity: ≥98%
Molecular Weight: 606.09
Molecular Formula: C20H24N3SCl•2C4H4O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Prochlorperazine, dimaleate is a phenothiazine antipsychotic, D2DR(D2 dopamine receptor) antagonist, and an antispasmodic gent; it is used in the treatment of spastic gastrointestinal disorders.


References

Dannenberg, A., Zakim, D., "Effects of proclorperazine on the function of integral membrane proteins." Biochem. Pharmacol., v. 37, 1259-1262 (1988).

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (slightly soluble 0.3 mg/ml), 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin (2.3 mg/ml), methanol, and DMSO (25 mM).
Storage :
Store at room temperature
Melting Point :
238-240° C
Refractive Index :
n20D ~1.62 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
SO3150000
PubChem CID :
5281032
Merck Index :
14: 7761
MDL Number :
MFCD00069330
EC Number :
201-511-3
SMILES :
CN1CCN(CC1)CCCN2C3=C(SC4=CC=CC=C24)C=CC(=C3)Cl.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Ghelardini Ghelardini, C. et al. (PubMed 15225680) reported that Prochlorperazine induces central antinociception mediated by the muscarinic system. -SCBT Publication Review
Date published: 2015-01-31
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