PrednisoloneAn antiinflammatory, immunosuppressive glucocorticoid

Prednisolone (CAS 50-24-8)

Prednisolone | CAS 50-24-8 is rated 5.0 out of 5 by 1.
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Synonym: Meticortelone; Metacortandralone; Deltacortril
Application: An antiinflammatory, immunosuppressive glucocorticoid
CAS Number: 50-24-8
Molecular Weight: 360.44
Molecular Formula: C21H28O5
* Refer to Certificate of Analysis for lot specific data (including water content).
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Prednisolone is a glucocorticoid with antiinflammatory and immunosuppressive activity in rabbits. It induces apoptosis in eosinophiles and colon cancer cell lines.


References

1. Fan, G K., et al., 2000. Eosinophilic apoptosis in sinus mucosa: relationship to tissue eosinophilia and its resolution in allergic sinusitis. The Journal of allergy and clinical immunology. 106(3): 551-8. PMID: 10984377
2. Ma, G., et al., 2000. Treatment of murine angiosarcoma with etoposide, TNP-470 and prednisolone. Journal of dermatological science. 24(2): 126-33. PMID: 11064248
3. Meng, R D., et al., 2001. p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma. Experimental cell research. 262(2): 154-69. PMID: 11139340

Physical State :
Solid
Solubility :
Slightly soluble in water
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5755
SMILES :
C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO

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Certificate of Analysis

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Rated 5 out of 5 by from Meng et al Meng et al. (PubMed ID 11139340) founf that prednisoione induced apoptosis in glioblastoma, ovarian cancer, and colon cancer cell lines. -SCBT Publication Review
Date published: 2015-01-03
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