PrazobindCAS: 107021-36-3
MF: C23H27N5O3
MW: 421.49
An α1-Adrenoceptor alkylating reagent.

Prazobind (CAS 107021-36-3)

Prazobind | CAS 107021-36-3 is rated 5.0 out of 5 by 1.
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Application: An α1-Adrenoceptor alkylating reagent
CAS Number: 107021-36-3
Molecular Weight: 421.49
Molecular Formula: C23H27N5O3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Prazobind is an α1-Adrenoceptor alkylating reagent that is also a Prazosin analog. It exhibits antihypertensive properties.


References

Piascik, M.T., et al.: J. Pharmacol. Exp. Ther., 251, 878 (1989), Pitha, J., et al.: J. Med. Chem., 32, 96 (1989), Mante, S., et al.: Eur. J. Pharmacol., 208, 113 (1991),

Physical State :
Solid
Solubility :
Soluble in Chloroform, DMSO, Ethanol and Methanol
Storage :
Store at 4° C
Melting Point :
245-247°C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
4892
SMILES :
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC5CCC4C=C5)N)OC

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from FIglewicz et al FIglewicz et al. (PubMed ID 1653632) found that prazobind inactivated the alpha 1-adrenergic receptor and blocked insulin stimulation of inositol phosphate 1 accumulation in the rat hippocampus. -SCBT Publication Review
Date published: 2015-07-18
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