PPM-18Anti-inflammatory agent shown to block of NF kappa B

PPM-18 (CAS 65240-86-0)

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Synonym: N-(1,4-dihydro-1,4-dioxo-2-naphthalenyl)-benzamide
Application: Anti-inflammatory agent shown to block of NF kappa B
CAS Number: 65240-86-0
Purity: >97%
Molecular Weight: 277.3
Molecular Formula: C17H11NO3
* Refer to Certificate of Analysis for lot specific data (including water content).
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PPM-18 is a cell-permeable and anti-inflammatory agent shown to express inhibitory effects of iNOS through the blocking of NF kappa B activation in vitro. However, experiments have shown that the enzymatic effects of iNOS and eNOS were not directly affected. it also is an histone deacetylase (HDAC) inhibitor.

Physical State :
Solid
Solubility :
Soluble in DMSO
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
4882
SMILES :
C1=CC=C(C=C1)C(=O)NC2=CC(=O)C3=CC=CC=C3C2=O

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Certificate of Analysis

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