PPHP (CAS 87864-20-8)
Alternate Names:
5-phenyl-4E-pentenyl-1-hydroperoxide
Application:
PPHP is a peroxide used to assay peroxidase activity
CAS Number:
87864-20-8
Purity:
>98%
Molecular Weight:
178.2
Molecular Formula:
C11H14O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PPHP, 5-phenyl-4-pentenyl-1-hydroperoxide, is a small molecule peroxide employed as a substrate probe for peroxidase enzymes. Conversion of PPHP to 5-phenyl-4-pentenyl alcohol by peroxidase enzymes can be traced with HPLC to assay peroxidase activity. This approach has been exploited to assay the activity of COX-1 and COX-2, and can be used to identify and characterize other peroxide-reducing enzymes.
References
1. Weller, P.E., et al. 1985. Arch. Biochem. Biophys. 243: 633-643. PMID: 4083906
2. Odenwaller, R., et al. 1992. J. Biol. Chem. 267: 13863-13869. PMID: 1321128
3. Duggan, K.C., et al. 2010. Methods Mol. Biol. 644: 55-65. PMID: 20645165
Formulation
:
A solution in ethanol
Physical State
:
Liquid
Storage
:
Store at -20° C
Boiling Point
:
78° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID
:
MDL Number
:
MFCD00216135
SMILES
:
C1=CC=C(C=C1)/C=C/CCCOO
Download SDS (MSDS)
Certificate of Analysis
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