PPHP CAS: 87864-20-8
MF: C11H14O2
MW: 178.2
A peroxide used to assay peroxidase activity.

PPHP (CAS 87864-20-8)

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Alternate Names: 5-phenyl-4E-pentenyl-1-hydroperoxide
Application: PPHP is a peroxide used to assay peroxidase activity
CAS Number: 87864-20-8
Purity: >98%
Molecular Weight: 178.2
Molecular Formula: C11H14O2
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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PPHP, 5-phenyl-4-pentenyl-1-hydroperoxide, is a small molecule peroxide employed as a substrate probe for peroxidase enzymes. Conversion of PPHP to 5-phenyl-4-pentenyl alcohol by peroxidase enzymes can be traced with HPLC to assay peroxidase activity. This approach has been exploited to assay the activity of COX-1 and COX-2, and can be used to identify and characterize other peroxide-reducing enzymes.


References

1. Weller, P.E., et al. 1985. Arch. Biochem. Biophys. 243: 633-643. PMID: 4083906
2. Odenwaller, R., et al. 1992. J. Biol. Chem. 267: 13863-13869. PMID: 1321128
3. Duggan, K.C., et al. 2010. Methods Mol. Biol. 644: 55-65. PMID: 20645165

Formulation :
A solution in ethanol
Physical State :
Liquid
Storage :
Store at -20° C
Boiling Point :
78° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD00216135
SMILES :
C1=CC=C(C=C1)/C=C/CCCOO

Download SDS (MSDS)

Certificate of Analysis

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