PPACK dihydrochloride, biotinylatedA thrombin and tPA inhibitor

PPACK dihydrochloride, biotinylated

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Synonym: Biotin-X-D-Phe-Pro-Arg-chloromethylketone, 2HCl
Application: A thrombin and tPA inhibitor
Molecular Weight: 979.5
Molecular Formula: C43H70N10O7SCl•2HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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PPACK dihydrochloride, biotinylated, is a biotin-X-analog of PPACK dihydrochloride (sc-201291). It acts as a specific probe for active serine proteases and a potent inhibitor of thrombin and tissue plasminogen activator (tPA). PPACK dihydrochloride, biotinylated, is useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.


References

1. Williams, E B., et al., 1989. Zymogen/enzyme discrimination using peptide chloromethyl ketones. The Journal of biological chemistry. 264(13): 7536-45. PMID: 2708377

Formulation :
In 10 mM HCl
Physical State :
Liquid
Storage :
Store at -20° C
IC50 :
thrombin: IC50 = 110 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Download SDS (MSDS)

Certificate of Analysis

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