PPACK dihydrochloride, biotinylated, is a biotin-X-analog of PPACK dihydrochloride (sc-201291). It acts as a specific probe for active serine proteases and a potent inhibitor of thrombin and tissue plasminogen activator (tPA). PPACK dihydrochloride, biotinylated, is useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.
1. Williams, E B., et al., 1989. Zymogen/enzyme discrimination using peptide chloromethyl ketones. The Journal of biological chemistry. 264(13): 7536-45. PMID: 2708377
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