(±)-Bisoprolol hemifumarateCAS: 104344-23-2
MF: C18H31NO4 ½C4H4O4
MW: 383.48
A selective β1-AR antagonist.

(±)-Bisoprolol hemifumarate (CAS 104344-23-2)

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Application: A selective β1-AR antagonist
CAS Number: 104344-23-2
Purity: >98%
Molecular Weight: 383.48
Molecular Formula: C18H31NO4 ½C4H4O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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(±)-Bisoprolol hemifumarate is a selective β1-AR adrenergic antagonist. Possesses β1/β2 selectivity of approximately 100-fold and a Kd of 2-3 nM at the β1-AR (β1 receptor).


References

1. Kaumann, A.J. and Lemoine, H. 1985. Naunyn Schmiedebergs Arch.Pharmacol. 331: 27-39. PMID: 2866449
2. Klockow, M., et al. 1986. Arzneimittelforschung. 36: 197-200. PMID: 2870719

Physical State :
Solid
Solubility :
Soluble in water (50 mM), ethanol, methanol, and chloroform.
Storage :
Store at 4° C
Melting Point :
100-104° C
Boiling Point :
445° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.5 (Predicted)
IC50 :
Plasmodium falciparum : IC50 = 3.16 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
UB8390000
PubChem CID :
62955
Merck Index :
14: 1295
MDL Number :
MFCD00792743
SMILES :
CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O.CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O.C(=CC(=O)O)C(=O)O

Download SDS (MSDS)

Certificate of Analysis

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