PKC ζ Pseudo-substrate inhibitor InhibitorA selective inhibitor of PKC ζ

PKC ζ Pseudo-substrate inhibitor Inhibitor

PKC ζ Pseudo-substrate Inhibitor is rated 5.0 out of 5 by 1.
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Synonym: SIYRRGARRWRKL; Protein Kinase Cζ/ι; Pseudosubstrate Inhibitor
Application: A selective inhibitor of PKC ζ
Purity: ≥97% (HPLC)
Molecular Weight: 1718
Molecular Formula: C76H128N30O16
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

PKCζ Pseudo-substrate inhibitor is a selective, reversible and substrate-competitive inhibitor of protein kinase Cζ and protein kinase C (PKCζ/ι) isozymes.


References

1. Standaert, M.L. et al. 1997. J. Biol. Chem. 272(48): 30075-30082. PMID: 9374484

2. Laudanna, C. et al. 1998. J. Biol. Chem. 273(46): 30306-30315. PMID: 9804792

3. Sajan, M.P. et al. 1999. J. Biol. Chem. 274(43): 30495-30500. PMID: 10521430

Usage :
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Physical State :
Solid
Sequence :
H-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-OH
Solubility :
Soluble in water or acetic acid.
Storage :
Desiccate at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Download SDS (MSDS)

Certificate of Analysis

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PKC ζ Pseudo-substrate inhibitor Inhibitor  Product Citations

See how others have used PKC ζ Pseudo-substrate inhibitor Inhibitor. Click on the entry to view the PubMed entry .

Citations 1 to 9 of 9 total

PMID: # 29914450  MacDonald, AF.|Bettaieb, A.|Donohoe, DR.|Alani, DS.|Han, A.|Zhao, Y.|Whelan, J.| et al. 2018. BMC Complement Altern Med. 18: 188.

PMID: # 29497043  2018. Cell Death Dis. 9: 340.

PMID: # 27131825  2016. Environ. Pollut. 214: 646-56.

PMID: # 25355318  Wang, Y. et al. 2014. The Journal of biological chemistry. 289: 35795-805.

PMID: # 20307614  Li, L. et al. 2010. Peptides. 31: 1159-1164.

PMID: # 20388485  2010. Arch. Biochem. Biophys. 498: 57-61.

PMID: # 19706599  Gayen, JR. et al. 2009. The Journal of biological chemistry. 284: 28498-509.

PMID: # 15721486  2005. Regul. Pept. 128: 43-50.

Citations 1 to 9 of 9 total

Is this product membrane permeable? Thank you!

Asked by: Jz28sail
Thank you for your question. sc-3098, PKC ζ Pseudo-substrate inhibitor is not membrane permeable. If your protocol requires a membrane permeable PKC ζ Pseudo-substrate inhibitor, we recommend sc-397537, PKC ζ Pseudo-substrate inhibitor, Myristoylated (https://www.scbt.com/scbt/product/pkc-zeta-pseudo-substrate-inhibitor-myristoylated?requestFrom=search)
Answered by: Chemical Support 5
Date published: 2017-04-07
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Rated 5 out of 5 by from Gayen Gayen, et al. (PubMed ID 19706599) used product sc-3098, PKC Pseudo-substrate, to characterize PKC isoform specificity of PST (pancreastatin) using HepG2 cells. -SCBT Publication Review
Date published: 2015-06-21
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