PITSLRE Antibody (B-9) is a mouse monoclonal IgM (kappa light chain) provided at 200 µg/ml
specific for an epitope mapping between amino acids 749-775 at the C-terminus of PITSLRE A of human origin
recommended for detection of PITSLRE A and PITSLRE B of human origin and PITSLRE of mouse and rat origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
blocking peptide, sc-377296 P
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of PITSLRE (B-9): sc-377296.
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The PITSLRE β1 protein, a distantly related member of the Cdk family of protein kinases, induces apoptosis after low levels of ectopic expression. Apoptosis, or programmed cell death, is similarly induced by ectopic expression of an amino terminal deletion mutant retaining the catalytic and carboxy terminal domains of PITSLRE β1, but not by other mutants lacking histone H1 kinase activity or by other Cdk family members. The terminology for the ten isoforms of the PITSLRE subfamily of proteins is based on the conserved PSTAIRE box region of Cdc2 p34. Depending on which of the PITSLRE genes produce the protein, the cDNA and protein are designated α, β or γ (i.e., PITSLRE A gene, α; PITSLRE B gene, β and PITSLRE C gene, γ). Some of the isoforms such as PITSLRE α1 (T cells) and PITSLRE β1 (B cells and brain), are expressed in specific cell types, while others are expressed ubiquitously.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.