Piperine is an alkaloid from black pepper that shows chemopreventive, cytotoxic, anti-inflammatory, and antioxidant effects. It is suggested that piperine exerts its chemopreventive effect by augmenting antioxidant defense system and modulating lipid peroxidation.
Sunila ES, Kuttan G. J Ethnopharmacol. 90:339-46 (2004). Selvendiran K, Senthilnathan P, Magesh V et al. Phytomedicine. 11:85-9 (2004). Mittal R, Gupta RL. Methods Find Exp Clin Pharmacol. 22:271-4 (2000).
Soluble in ethanol (57 mg/ml), DMSO (57 mg/ml), alcohol (66.67 mg/ml), chloroform (588.24 mg/ml), and ether (27.78 mg/ml).
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