Phytic acid hexabarium salt CAS: 90940-73-1
MF: C6H6Ba6O24P6
MW: 1471.90
A potent chelator of divalent and trivalent cations.

Phytic acid hexabarium salt (CAS 90940-73-1)

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Alternate Names: Inositol hexakisphosphate
Application: Phytic acid hexabarium salt is a potent chelator of divalent and trivalent cations
CAS Number: 90940-73-1
Molecular Weight: 1471.90
Molecular Formula: C6H6Ba6O24P6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Phytic acid is present in all eukaryotic cells and in plants, it is known to function as a [PO4]3- storage depot and precursor for other inositol phosphates and pyrophosphates. Its high surface negative charge makes it a potent chelator of divalent and trivalent cations in vitro, and it is most likely associated with Ca2+ or Mg2+ ions in vivo. In yeast, phytic acid acts with the nuclear pore protein Gle1 to regulate the nuclear export of mRNA by coactivating the RNA-dependent ATPase activity of DExD-box protein 5 (Dbp5).


References

Shears, S.B., Assessing the omnipotence of inositol hexakisphosphate. Cell. Signal. 13, 151-158, (2001); Raboy, V., myo-Inositol-1,2,3,4,5,6-hexakisphosphate. Phytochemistry 64, 1033-1043, (2003); Weirich, C.S., et al., Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export. Nat. Cell Biol. 8, 668-676, (2006); Alcazar-Roman, A.R., et al., Inositol hexakisphosphate and Gle1 activate the DEAD-box protein Dbp5 for nuclear mRNA export. Nat. Cell Biol. 8, 711-716, (2006)

Physical State :
Solid
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
SMILES :
[Ba].OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O

Download SDS (MSDS)

Certificate of Analysis

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