Phloxine BA fluorescein photoactive dye

Phloxine B (CAS 18472-87-2)

Phloxine B | CAS 18472-87-2 is rated 5.0 out of 5 by 1.
  • y_2019, m_10, d_11, h_18
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_203753, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 89ms
  • REVIEWS, PRODUCT
5
1
4
0
3
0
2
0
1
0
Synonym: Acid Red 92; Cyanosine
Application: A fluorescein photoactive dye
CAS Number: 18472-87-2
Molecular Weight: 829.63
Molecular Formula: C20H2Br4Cl4O52Na
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Phloxine B is a fluorescein dye which is known to inhibit the enzyme UDP-glucuronosyltransferase (UGT), the main catalyst for the glucuronidation of 7-HC. Additionally, Phloxine B is reported to be a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. As a photoactive dye, Phloxine B is reported to have efficacy against gram-positive organisms. Phloxine B has also been utilized in a study investigating the visible light-induced photodegradation kinetics when coated onto silica TLC plates and in solution. The rapid photodegradation of Phloxine B via visible light exposure was noted and the phototoxicity of the remaining residues were also reported to be decreased.


References

1. Slabbert, J.C., et al. 1990. J Esthet Dent. 2: 177-180. PMID: 2088435
2. Wang, H., et al. 2008. Biomed. Environ. Sci. 21: 438-441. PMID: 19133619
3. Brovko, L.Y., et al. 2009. J. Food Prot. 72: 1020-1024. PMID: 19517729
4. van Midwoud, P.M., et al. 2010. Anal. Chem. [Epub ahead of print]. PMID: 21128611

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (1 mg/ml) (clear red solution).
Storage :
Store at room temperature
pK Values :
pKa: 1.32
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
LM5900000
PubChem CID :
6433718
Merck Index :
14: 10471
MDL Number :
MFCD00070627
EC Number :
242-355-6
Beilstein Registry :
3887100
SMILES :
C1=C2C(=C(C(=C1Br)[O-])Br)OC3=C(C(=C(C=C3C24C5=C(C(=C(C(=C5Cl)Cl)Cl)Cl)C(=O)O4)Br)[O-])Br.[Na+].[Na+]

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Phloxine B  Product Citations

See how others have used Phloxine B. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 22291963  Tanae, K. et al. 2012. PLoS ONE. 7: -.

Citations 1 to 1 of 1 total

are you selling to Russia producer?

Asked by: Elmira
Thank you for your question. I am not sure what you are asking, but we do have distributors in Russia, please reach out to them for further information. You can find them here: https://www.scbt.com/resources/distributors
Answered by: Tech Service
Date published: 2019-09-23
  • y_2019, m_10, d_12, h_17CST
  • bvseo_bulk, prod_bvqa, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_203753, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 92ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Van Midwoud et al Van Midwoud et al. (PubMed ID 21128611) showed that Phloxine B showed a concentration-dependent inhibition of 7-HC glucuronide formation and allowed the calculation of an IC50 value using one single liver slice. -SCBT Publication Review
Date published: 2015-05-25
  • y_2019, m_10, d_11, h_18
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.13
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_203753, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 21ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.