PF 4800567 CAS: 1188296-52-7
MF: C17H18ClN5O2
MW: 359.81
A selective inhibitor of casein kinase 1ε.

PF 4800567 (CAS 1188296-52-7)

PF 4800567 | CAS 1188296-52-7 is rated 5.0 out of 5 by 1.
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Alternate Names: 3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin- 4-amine
Application: PF 4800567 is a selective inhibitor of casein kinase 1ε
CAS Number: 1188296-52-7
Purity: ≥98%
Molecular Weight: 359.81
Molecular Formula: C17H18ClN5O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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PF 4800567 is a selective casein kinase 1ε inhibitor. PF 4800567 displays a 22-fold greater potency towards CK1ε than CK1δ (IC50 values are 32 and 711 nM for CK1ε and CK1δ respectively).

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM).
Storage :
Store at 4° C
IC50 :
CK1ε: IC50 = 32 nM; CK1δ: IC50 = 711 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD20926348
SMILES :
C1COCCC1N2C3=C(C(=N2)COC4=CC(=CC=C4)Cl)C(=NC=N3)N

Download SDS (MSDS)

Certificate of Analysis

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Can I store this long term after solubilizing in DMSO?

Asked by: SCchem16
Thank you for your question. PF 4800567, sc-362782, dissolved in DMSO is okay in the refrigerator for several days but can be stored at -20 ºC or cooler for several months. However, we always recommend using solutions the same day.
Answered by: TechService7
Date published: 2017-02-13
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Rated 5 out of 5 by from Bryant et al Bryant et al. ({PubMed ID 22089318) found that the Csnk1e inhibitor, PF 4800567, elevated mice locomotor stimulant response to both methamphetamines and fentanyl. -SCBT Publication Review
Date published: 2015-07-07
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