PF-2545920An inhibitor of phosphodiesterase 10A

PF-2545920 (CAS 1292799-56-4)

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Synonym: 2-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenoxy)methyl)quinoline
Application: An inhibitor of phosphodiesterase 10A
CAS Number: 1292799-56-4
Purity: ≥98%
Molecular Weight: 392.45
Molecular Formula: C25H20N4O
* Refer to Certificate of Analysis for lot specific data (including water content).
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PF-2545920 is a potent and selective inhibitor of phosphodiesterase 10A (PDE10A) (IC50 = 0.37 nM). This compound inhibits the ability of PDE10A to break down cAMP and cGMP, which are secondary messenger molecules that play an important role in signal transduction.

Physical State :
Solid
Storage :
Store at -20° C
Melting Point :
~250.10° C (Predicted)
Boiling Point :
~580.29° C at 760 mmHg (Predicted)
Density :
~1.2 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
11581936
SMILES :
CN1C=C(C(=N1)C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)C5=CC=NC=C5

Download SDS (MSDS)

Certificate of Analysis

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What is the solubility of the compound in DMSO?

Asked by: two2igm05
Thank you for your question. The solubility of PF-2545920, sc-364355, in DMSO is 78 mg/mL warmed (198.75 mM).
Answered by: Chemical Support 4
Date published: 2017-03-21
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